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 Feline immunodeficiency virus (FIV)

FIV is a lentivirus which is very similar to HIV and cause AIDS like disease in cats. [From 2.5% up to 4.4% of cats worldwide, and about 2.5% of cats in the USA, are infected with FIV ].FIV is highly species-specific and infects only felines. FIV is very small around 80-100nm in diameter of virions. virus is deploid in structure,gag,poland env are the commonly present gene. It is comparatively less complex structure than the HIV.

[FIV is the only non-primate lentivirus to cause an AIDS-like syndrome, but FIV is not typically fatal for cats, as they can live relatively healthily as carriers and transmitters of the disease for many years. A vaccine is available although its efficacy remains uncertain, and cats will test positive for FIV antibodies after vaccination.]

Its primary mode of transmission is through bite wounds unlike sexual contact in case of other similar viruses like HIV. The bioinformtics analysis of FIV provide scope for enhancing the current knowledge of immunodeficiency viruses specifically of HIV.


Cornell Feline Health Center : http://www.vet.cornell.edu/fhc/brochures/fiv.html

ValÚria Maria Lara, Sueli Akemi Taniwaki, JoŃo Pessoa Ara˙jo J˙nior (2008), Occurrence of feline immunodeficiency virus infection in cats" doi:  10.1590/S0103-84782008000800024

Richards,"Feline immunodeficiency virus vaccine: Implications for diagnostic testing and disease management"

doi: 10.1016/j.biologicals.2005.08.004 , PMID 16257536.

Zislin, "Feline immunodeficiency virus vaccine: A rational paradigm for clinical decision-making", doi: 10.1016/j.biologicals.2005.08.012  , PMID 16257537.

 More Resources:

Cornell Feline Health Center   http://www.vet.cornell.edu/fhc/brochures/fiv.html

Might, Jennifer Lynne (2004), Feline Immunodeficiency Virus (FIV),  http://www.blackgiraffe.com/jmight/fiv/fiv.html, retrieved 2006-01-23